No. 2003 Plenary talk Family name : Knuteson Given name : Bruce Affiliation : Massachusetts Institute of Technology Abbreviation : MIT E-mail address : knuteson@mit.edu Title : Systematic Analysis of Frontier Energy Collider Data Abstract : The current generation of frontier energy colliders presents an excellent opportunity for discovering physics beyond the Standard Model. Unfortunately, predictions for what that new physics may be are all over the map. How can we search for new physics when we only vaguely know what it should look like? Is there a way to perform an unbiased yet data-driven search? Can we quantify the "interestingness" of apparent anomalies after looking at the data? Is it possible to set up a framework that systematizes and subsumes the current shotgun approach to model-testing, and enhances our chances of convincingly demonstrating evidence of new physics in Tevatron or LHC data? SLEUTH is a strategy that answers these and related questions. QUAERO is a web-based tool that automates the final steps of analyses at frontier energy colliders. It has been designed with the goals of expunging exclusion contours from conference talks, obviating the necessity of "uncorrecting" experimental results, reducing human bias in experimental measurements, reducing by orders of magnitude the time required to perform analyses, allowing the publication of collider data in their full dimensionality, rigorously propagating systematic errors, dramatically increasing the robustness of experimental results, and facilitating the combination of results among different experiments. QUAERO has been used to make a subset of D0 Run I data publicly available, and is being explored as a means of putting LEP data at your fingertips. Key enabling ideas include an efficient heuristic for variable selection, a fast non-parametric density estimator, a prescription for optimal binning, an orthogonal partitioning of the data, and a convenient means of handling systematic errors.